性别:女
职称: 副教授 硕士研究生导师
电子邮件: [email protected]
学科方向: 071004-水生生物学
2026年招收水生生物学学术硕士1名
研究方向
（1）对虾先天免疫与病原互作；
（2）对虾免疫与生长调控机制。
个人经历
2010-2014，中山大学，免费成人直播
，理学学士
2014-2019，中山大学，免费成人直播
，理学博士
2019-2021，中山大学，海洋科学学院，博士后
2021-2023，中山大学，海洋科学学院，特聘副研究员
2023-至今，中山大学，免费成人直播
，副教授
学术成就
从事对虾先天免疫通路与病原互作研究，共发表SCI收录论文40篇，以第一作者/通讯作者发表论文14篇。（1）揭示对虾MAPK通路介导WSSV爆发的新机制（2）阐明以对虾抗弧菌免疫网络。（3）解析对虾抗细菌免疫与对虾生长的协同/拮抗机制。
承担课题
主持国家自然科学基金2项，十四五国家重点研发计划子课题1项，广东省自然科学基金3项，中国博士后科学基金特别资助1项，广州市项目1项。
近年论文专著
Xiaodi Wang, Hejia Chen, Ruiying Li, Hao Yang, Airong Lv, Zhengkai Dong, Yaoxing Long, Haoyang Li, Chaozheng Li, Jianguo He*, Sheng Wang*, FRAT2 in Litopenaeus vannamei activates Wnt/β-catenin and JNK/c-Jun signaling pathways to enhance antibacterial immunity, Aquaculture, 2026, 611, 743088
Sheng Wang*, Xiaodi Wang, Hao Yang, Xuanzheng Di, Haoyang Li, Bin Yin, Ziwei Liu, Chaozheng Li*, Jianguo He*, LRP6 regulates growth in Litopenaeus vannamei via the Wnt/β-catenin signaling pathway, Aquaculture Reports, 2025, 42, 102769
Sheng Wang, Haoyang Li, Qinyao Li, Bin Yin, Sedong Li, Jianguo He, Chaozheng Li. Signaling events induced by lipopolysaccharide-activated Toll in response to bacterial infection in shrimp, Frontiers in Immunology, 2023, 14,1119879.
Sheng Wang, Mingyu He, Qinyao Li, Haoyang Li, Bin yin, Jianguo He*, Chaozheng Li*.Rap2a is negatively regulated by NF-κB and contributes to growth via Wnt pathway in shrimp [J]. Frontiers in Marine. Science. 2022,9:942009
Sheng Wang, Haoyang Li, Rongjian Chen, Xiewu Jiang, Jianguo He, Chaozheng Li*. TAK1 confers antibacterial protection through mediating the activation of MAPK and NF-κB pathways in shrimp.Fish & Shellfish Immunology. 2022 Apr;123:248-256.
Sheng Wang, Haoyang Li, Peng Zhu, Qihui Fu, Bin Yin, Qinyao Li, Rongjian Chen, Xiewu Jiang, Shaoping Weng, Jianguo He*, Chaozheng Li*. MAPKKK15 gene from shrimp Litopenaeus vannamei is transcribed in larva development stages and contributes to WSSV pathogenesis [J]. Aquaculture, 2021.735324
Sheng Wang, Haoyang Li, Shaoping Weng, Chaozheng Li, Jianguo He. White spot syndrome virus establishes a novel IE1/JNK/c-Jun positive feedback loop to drive replication. Wang Sheng et al. iScience, 2020, 100752
Chaozheng Li#, Sheng Wang#, Jianguo He. The two NF-κB pathways regulating bacterial and WSSV infection of shrimp. Frontier in Immunology. 2019 Jul 30;10:1785
